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Systemic lupus erythematosus manifestation following COVID?19 infection: A coincidental or causal relation

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Case Report

Author Details : Muhammed Hajmusa*, Raza Ali Akbar

Volume : 1, Issue : 1, Year : 2022

Article Page : 46-48

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Abstract

Several intricate interactions of environmental and genetic factors can lead to autoimmune conditions in susceptible hosts. Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease which can be triggered or exacerbated by infection or infectious reactions. The causal link between infections and autoimmunity has been established through clinical studies. Although several viral infections have been associated with SLE, yet the impact of COVID-19 on SLE onset and flares has not been well established. We report a young female who developed new-onset SLE shortly after having COVID-19 infection. Her clinical and lab parameters were highly suggestive of SLE and she responded to standard medical therapy. We also briefly discuss the pathogenetic mechanisms of autoimmunity in cases of viral infections.

Keywords: Autoimmunity, Covid-19, Severe acute respiratory syndrome coronavirus 2, Systemic lupus erythematosus

How to cite : Hajmusa M, Akbar R A, Systemic lupus erythematosus manifestation following COVID?19 infection: A coincidental or causal relation. Yemen J Med 2022;1(1):46-48

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